Autophagy, as a conservative lysosomal degradation pathway, has been well studied for its multiple functions in the immune system. Autophagy has been gradually explored for the regulation of immune cell differentiation. In order to explore the specific mechanism, it is necessary to summarize the role of autophagy in the proliferation and differentiation of immune cells. It is summarized the effects of autophagy in some researches on the function and
differentiation of immune cells by introducing the function of autophagy selective degradation. In this review, we discuss the effect of autophagy in the differentiation of immune cells.
1.1. Background: Mycoplasma pneumonia is a common community pathogen associated with lower respiratory tract infection. Atypical progression of infected patients is rare but warrants particular attention, including searching for thrombosis and pulmonary embolism, especially in patients with atypically deteriorating respiratory status or prolonged progression of their symptoms.
Early Myoclonic Epileptic Encephalopathy in a Newborn: Successfully Control Seizures and Suppression-Burst EEG with Levetiracetam
Early epileptic encephalopathy with Suppression-Burst (SB) inElectroencephalography (EEG) comprises two epileptic syndromes, Early Infantile Epileptic Encephalopathy (EIEE) and Early Myoclonic Encephalopathy (EME). The SB EEG abnormalities are believed to contribute to the progressive disturbance in cerebral function.
We report a 3-month-old male infant who had two meningitis events with Citrobacter koseri and was eventually diagnosed as having a spinal dermal sinus tract. Recurrent meningitis is rare but fatal in newborns, and congenital spinal dermal sinus tracts are considered a crucial factor.
1.1. Introduction: Lymphangioma is an uncommon benign tumor believed to be the result of diffuse proliferation of lymphatic tissues. Abdominal lymphangiomatosis is a rare disease characterized by infiltration of the intraperitoneal organs with lymphangiomas. Clinical symptoms of this condition are not clear. Pathological, radiological, and clinical evidence are limited for diagnosis. During operation, it can be observed accidentally. Hereby, it may be an inconvenient instance for surgeons.
A 28 years female presented with a DJ stent coming out through the urethra. On examination part of DJ stent was lying outside urethra. She gave a history of URS done 2 years back for ureteric stone. She has been advised about DJ stent removal but she forgot. Blood investigations were normal. Xray KUB was suggestive of an encrusted DJ stent lying inside the urinary bladder. She was taken to operation theatre and laser Cystolithotripsy with the retrieval of DJ stent was done. The postoperative period was uneventful.
Herpes simplex virus can have many ocular manifestations, some of which are serious and vision-threatening with the potential to be chronic and recurrent, as well.
Psychosocial factors in substance use have generally been investigated by several researchers. There is little research on use of cannabis which appears to be increasing in recent times in developing countries such as Nigeria. This study examined personality, self-esteem and gender as factors in cannabis use.
Social Support, Religious Commitment, Hardiness and Psychological Well-Being of Psychiatric Patients’ Caregivers: A Nigerian Study
Research evidence indicates that religious commitment and social support has impact on mental health across diverse population, Impact of social support and religious commitment of Psychiatric patients’ caregivers has been give little research attention in Nigeria. The present study examined the association of social support, hardiness and religious commitment on psychological well-being of psychiatric patients’ caregivers.
PCOD could be an advanced heterogenous metabolic disorder affecting 10% of women at their fertile age. A well effective treatment for a complete cure for PCOD is still a challenge and evaluation of new strategies to treat this disease is of great priority. This review focuses on two aspects of PCOD, such as types of rodent screening models and diagnosis of major symptoms. A fully convincing animal model to study PCOD is still in challenge as they are multi-ovular species. But in many ways the rodent models are similar to human PCOD. This study explores on the parallels and problems associated with the use of different rodent models. Oligo- or anovulation, clinical or biochemical hyperandrogenism and polycystic ovaries represent the key clinical options on that the diagnosing ought to be primarily based. Determination of diagnosis parameters such as estrus cyclicity, insulin sensitivity, lipid profile, anti-oxidant status, weights of reproductive system and histopathological features of ovary were discussed along with the currently available treatment methods for PCOD.