Volume 6

Volume 6

Salvage Laparoscopic Radical Prostatectomy in Nonmetastatic Castration- Resistant Prostate Cancer: 2 Years Follow-Up and Current Evidence

Research Article

1. Abstract
1.1. Objective: To analyze the perioperatory and short-oncological outcomes in 5 cases with castration recurrent prostate pancer without metastasis [CRPC M0] developed after prostatic radiotherapy [pRT] and androgenic deprivation therapy [ADT] who underwent salvage laparoscopic RP [sLRP] with two years follow-up and review the current evidence.
1.2. Material and Methods: Perioperatory and oncological outcomes were prospectively analyzed. Inclusion criteria were patients that had received pRT and ADT with posteriorly presented as a CRPC M0 in standard imagines and positron emission tomography coline [PET].

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A Case of External Ear and Submandibular Extracranial Arteriovenous Malformation

Case Report

1. Abstract
1.1. Introduction
Arteriovenous malformation (AVM) of the head and neck is a rare vascular anomaly but when present is persistent and progressive in nature due to failure of regression of primitive arteriovenous channels during 4th till 6th week gestation.
1.2. Objective
The aim of this case report is to show the progressiveness of an extracranial AVM of a patient over the course of 20 years.
2. Case Description
Encik F, 34 years old gentleman, first presented with a swelling at the left ear pinna since the age of 15 years old. Another swelling at the left cheek was also noted at 21 years old. A set of investigation was done at that time and he was diagnosed as extracranial AVM. At 33 years old, there was sudden blood spurting from left pinna and he rushed back to Hospital Shah Alam where the bleeding was arrested by compression. The whole left pinna was pulsating with post auricular, infraauricular and left submandibular pulsating mass measuring 2 x 3 cm.

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How Ketamine Helps Make Change Happen

Short Communication

1. Short Communication
The lateral habenula is a center of emotional processing. It is also known as the brain’s “disappointment center.” Specifically, the lateral
habenula focuses on emotions and feelings that are difficult. In 2017, a study revealed that the lateral habenula in depressed animals and humans functions abnormally and tends to “over fire” neurons, causing an overwhelming abundance of negative thoughts, feelings and essentially, a depressive episode. Increasing evidence indicates that the aberrant activity of the LHb is associated with depressive symptoms such as helplessness, anhedonia, and excessive negative focus. Ketamine is known to directly affect this area of the brain. And it may serve to “reset” the brain’s “disappointment center” and thus ease symptoms of depression and restore more normal processing of disappointment or emotional pain.

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Endoscopy- Surgery and Life Saver

Case Report

1. Abstract
1.1. Case report: We present a young male prisoner of twenty six years who intentionally ingested multiple foreign bodies and was admitted in a government hospital with complaint of pain abdomen and vomiting for last one week. He was symptomatically treated and on evaluation, X-ray abdomen revealed multiple radio-opaque foreign bodies. Hence, he was referred to our centre for Endoscopy. The patient was conscious, co-operative, afebrile, well oriented without any signs or symptoms of perforation or peritonitis. The patient was subjected to endoscopy which revealed multiple metallic foreign bodies and glass piece. It was a very tricky and risky endoscopy procedure which was completed within twenty minutes and sharp edged five metallic and one glass piece were successfully removed and thus major surgery was avoided and a precious life was saved.

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Neonatal Uro-Sepsis Presenting with a Prostatic Abscess in a 20 Day Old Baby

Case Report

1. Introduction
Urinary Tract Infection (UTI) is commonly seen in young infants and poses a serious problem. UTI in neonates (<30 days of age) is associated with bacteremia and can be associated with congenital anomalies of the kidneys and urinary tract. UTI affects approximately one in six febrile neonates ≤30 days of age and the prevalence of UTI in febrile infants <8 weeks of age is 13.6%. UTI in neonates have a male predominance; males are affected 2.5-times greater than females [1, 2].

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Colovesical Fistula, as a Manifestation of Cancer of the Left Colon: Case Presentation

Case Report

1. Abstract
1.1. Introduction: Colovesical fistulas are infrequent complications, being those of malignant origin unusual as etiology and often cause problems for their diagnosis.

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ADC Thresholds in the Discrimination of Indolent and Aggressive Orbital Adnexa Lymphoma

Case Report

1. Abstract
1.1. Aim: This study aims to determine whether ADC measurements allow discrimination of indolent (group A) from aggressive orbital lymphoma (group B) and how much ADC value can predict lymphoma subtype.
1.2. Methods: A retrospective two-armed cohort study including 32 orbital adnexa lymphoma (OAL) lesions evaluated by conventional magnetic resonance image (MRI) and DWI examination preceding histopathological lesion confirmation. DWI using single-shot echo-planar imaging with b factors of 0,400 and 800 sec/mm2 were performed on 3 Tesla MRI unit. Lymphomas were grouped into indolent or aggressive histopathological subtypes according to the Revised European-American Classification of Lymphoid Neoplasms (REAL). The groups minimum, maximum and percentiles of ADC values of indolent were compared to those of aggressive lymphoma subtype. Multiple receiver operating characteristic curve (ROC) analysis was performed for predicting aggressive OL.

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Complete Atrio-Ventricular Block Secondary to Focal Acute Myocarditis

Case Report

1. Abstract
We present a case of a 24 -year-old man with syncope due to transient complete atrio-ventricular block secondary to acute myocarditis involving only basal anterior interventricular septum. Atrio-ventricular block occurred with a localized left ventricular dysfunction assessed by cardiac magnetic resonance. Previous reports suggest that serious conduction disturbances in acute myocarditis are associated with severe myocardial necrosis. Conversely, in our patient only magnetic resonance allow us to detect a focal myocardial injury that may account for the transient disturbance of conduction system. The implantation of a permanent pacemaker in this setting may be delayed because of potentially reversible myocardial damage.

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Prognostic Value of Thyroid Profile on Disease Severity and Mortality in COVID-19

Research Article

1. Abstract
1.1. Background
Precise accurate triage of COVID-19 patients during hospitalization for early identification of individuals at risk of developing severe disease.
1.2. The Aim
Of this study was to evaluate thyroid function in patients with COVID-19.
1.3. Methods
Confirmed COVID-19 andnon-COVID-19 pneumonia patients (included as control group) admitted to cardiothoracic hospital, Minia University, Egypt, between March 2020 and Sept 2021without history of thyroid disease. We analyzed the ability of each parameter to predict mortality in participants. Further, evaluated whether the combination of FT3 level with APACHE-II score could improve the mortality prediction.
1.4. Results
TSH was lower than normal range in 56.7% (68/120) of patients with COVID-19. TSH and serum FT3 were significantly lower inCOVID-19 patients than healthy control and non-COVID-19 pneumonia patients. TSH and FT3 were lower in severe COVID-19 with statistical significance and both positively correlated with the severity. FT4 in COVID-19 patients was not significantly different from the control group. Patients in the lowest FT3tertile had significantly higher rates of mortality (18/40), mechanical ventilation (24/53.3) and intensive care unit admission (20/44.4). In univariate analysesFT3 remained the most significant independent predictor of death.

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From Knee MRI To Ventricular GIST – A Case Presentation of Benign Incidental Finding which Led To Severe Pathology. A Case Report

Case Report

1. Abstract
Bone marrow reconversion (BMR) is a replacement of yellow bone marrow for red bone marrow in adults. It can have numerous causes, including malignancy, edema, infection, anemia, and other diseases. We report a case in which BMR was found incidentally on MRI of the knee. The initial complaint in our patient was right knee pain, which led to the early diagnosis of gastrointestinal stromal tumor (GIST). Upper endoscopy and examination of CT revealed a polypoid mass in the antrum of the stomach. The patient underwent atypical gastrectomy with pathologic confirmation of GIST. We would like to emphasise that incidental findings on MRI should not be dismissed and that findings such as BMR can lead to early cancer detection.

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